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Symbol Name ID |
Kalrn
kalirin, RhoGEF kinase MGI:2685385 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Stroke |
| Disease(s) Associated with KALRN | |
| cerebral infarction |
| Mouse Phenotypes | nervous system phenotype |
abnormal pituitary secretion |
acromegaly |
abnormal hippocampus pyramidal cell morphology |
abnormal cerebral cortex pyramidal cell morphology |
decreased CNS synapse formation |
abnormal dendrite morphology |
abnormal neuromuscular synapse morphology |
abnormal action potential |
abnormal neuron physiology |
decreased excitatory postsynaptic current frequency |
reduced AMPA-mediated synaptic currents |
reduced long-term potentiation |
decreased miniature excitatory postsynaptic current frequency |
decreased prepulse inhibition |
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| Availability | Mouse Genotype | |||||||||||||||
| Kalrntm1.1Npl/Kalrntm1.1Npl | ||||||||||||||||
| Kalrntm1Ppen/Kalrntm1Ppen | ||||||||||||||||
| Kalrntm2.1Npl/Kalrntm2.1Npl | * | |||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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